Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

To contribute published user compound and/or population files, upload your files here: Upload Model Files

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You can use a * character as a wildcard at the end of a alphanumeric search term. The search term must start with at least one character before the wildcard. E.g., Rifam* will get you “Rifampicin” and “Rifampin”.
You can also use a * character as a wildcard in the middle of a alphanumeric search term. The search term must still start with at least one character before the wildcard. E.g., Rif*in will also get you “Rifampicin” and “Rifampin” .
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Found 141 Matches

Ceftibuten_V14R1_AstraZeneca_20200327

Model Files Publication

Ceftibuten for pediatric predictions.

Search Score: 1

Esomeprazole_V14R1_USFDA_20160711

Model Files Publication

Note: This compound file is for esomeprazole solution, not for delayed release esomeprazole formulations 2. V12R1 compound file built to simulate adult PK. Supplied file is a V14R1 file that has been tested to generate identical results under the condition of mutual interaction with R-omeprazole (Condition 2 in Table II in our publication).

Search Score: 1

Ganciclovir_V15R1_USFDA_20170810

Model Files Publication

http://onlinelibrary.wiley.com/doi/10.1002/cpt.750/full Ganciclovir compound file in healthy volunteers. Evaluation of the effect of renal impairment on the PK of OAT substrates. NOTE: Kp scaler in model should be 0.33, different from Table 1.

Search Score: 1

Methotrexate_RES_V17R1_Simcyp_20180228

Model Files Publication

Simcyp developed Methotrexate compound file. Compound summary included. This was developed as a research file and its current status and limitations are outlined in summary document.

Search Score: 1

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Ceftibuten_V14R1_AstraZeneca_20200327

Esomeprazole_V14R1_USFDA_20160711

Ganciclovir_V15R1_USFDA_20170810

Methotrexate_RES_V17R1_Simcyp_20180228

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