Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

To contribute published user compound and/or population files, upload your files here: Upload Model Files

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You can use a * character as a wildcard at the end of a alphanumeric search term. The search term must start with at least one character before the wildcard. E.g., Rifam* will get you “Rifampicin” and “Rifampin”.
You can also use a * character as a wildcard in the middle of a alphanumeric search term. The search term must still start with at least one character before the wildcard. E.g., Rif*in will also get you “Rifampicin” and “Rifampin” .
You can also use a * character as a wildcard at the start of a alphanumeric search term. However you must use forward slashes to delimit the search term and use a point before the wildcard. E.g., /.*picin/ will only get you “Rifampicin”.

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Found 141 Matches

Cidofovir_V12R1_FDA_20150709

Model Files Publication

Table 1 of main text, further discussion in supplemental file. Clarification: the value of intrinsic CL for hepatic elimination (0.41) is for undefined human liver microsomes according to retrograde calculation, with a unit of uL/min/mg. The operating hepatic CLint is driven by S9, which has a value of 0.13, obtained from sensitivity analysis to match HLM value above. This clarification will be informed to the journal.

Search Score: 1

Ceftazidime_V14R1_AstraZeneca_20200327

Model Files Publication

Ceftazidime for pediatric predictions.

Search Score: 1

Ondansetron_V14R1_AstraZeneca_20200427

Model Files Publication

Ondansetron adult compound file for paediatric prediction.

Search Score: 1

Nicotine_MechKiM_V16R1_UniversityOfManchester_20210421

Model Files Publication

https://doi.org/10.1124/jpet.118.251413 Nicotine compound file with MechKiM

Search Score: 1

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Cidofovir_V12R1_FDA_20150709

Ceftazidime_V14R1_AstraZeneca_20200327

Ondansetron_V14R1_AstraZeneca_20200427

Nicotine_MechKiM_V16R1_UniversityOfManchester_20210421

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