Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

To contribute published user compound and/or population files, upload your files here: Upload Model Files

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You can use a * character as a wildcard at the end of a alphanumeric search term. The search term must start with at least one character before the wildcard. E.g., Rifam* will get you “Rifampicin” and “Rifampin”.
You can also use a * character as a wildcard in the middle of a alphanumeric search term. The search term must still start with at least one character before the wildcard. E.g., Rif*in will also get you “Rifampicin” and “Rifampin” .
You can also use a * character as a wildcard at the start of a alphanumeric search term. However you must use forward slashes to delimit the search term and use a point before the wildcard. E.g., /.*picin/ will only get you “Rifampicin”.

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Found 141 Matches

DasabuvirRitonavirClopidogrelGlucuronide_V14R1_AbbVie_20200214

Model Files Publication

Workspace combines model files for Dasabuvir, Ritonavir, Clopidogrel and its glucuronide metabolite as published in Shebley et al., CPT, 2017 Note: The file was developed in V4R1, however the workspace cannot be open in V14R1 or V15R1, as it was last saved in V16. Therefore the fill can be opened only in Simcyp Simulator V16 and later.

Search Score: 1

Vancomycin_V14R1_AstraZeneca_20200327

Model Files Publication

Vancomycin for pediatric predictions. https://ascpt.onlinelibrary.wiley.com/doi/full/10.1002/psp4.12101

Search Score: 1

Avibactam_V15R1_USFDA_20170810

Model Files Publication

http://onlinelibrary.wiley.com/doi/10.1002/cpt.750/full Avibactam compound file in healthy volunteers. Evaluation of the effect of renal impairment on PK of OAT substrates

Search Score: 1

Emtricitabine_V18R1_Simcyp_20200212

Model Files Publication

https://www.ncbi.nlm.nih.gov/pubmed/31602556 FO, mainly renally excreted. Has been used for HV, Pregnancy population and elderly population.

Search Score: 1

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DasabuvirRitonavirClopidogrelGlucuronide_V14R1_AbbVie_20200214

Vancomycin_V14R1_AstraZeneca_20200327

Avibactam_V15R1_USFDA_20170810

Emtricitabine_V18R1_Simcyp_20200212

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