Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

To contribute published user compound and/or population files, upload your files here: Upload Model Files

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You can use a * character as a wildcard at the end of a alphanumeric search term. The search term must start with at least one character before the wildcard. E.g., Rifam* will get you “Rifampicin” and “Rifampin”.
You can also use a * character as a wildcard in the middle of a alphanumeric search term. The search term must still start with at least one character before the wildcard. E.g., Rif*in will also get you “Rifampicin” and “Rifampin” .
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Found 141 Matches

Meropenem_V14R1_AstraZeneca_20200327

Model Files Publication

Meropenem for pediatric prediction.

Search Score: 1

Sotalol_V14R1_ AstraZeneca_20200327

Model Files Publication

Sotalol for pediatric predictions.

Search Score: 1

Tramadol_V14R1_AstraZeneca_20200427

Model Files Publication

Tramadol adult compound file for pediatric prediction. The following parameters need to be updated, as compared to Table 2 in the manuscript: CYP2D6 0.7, CYP3A4 0.035, CYP2B6 0.1, CLr 6.6 L/hr

Search Score: 1

Lamivudine_V18R1_Simcyp_20200212

Model Files Publication

FO, mainly renally excreted. Has been used with HV, pregnancy population and elderly population.

Search Score: 1

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Meropenem_V14R1_AstraZeneca_20200327

Sotalol_V14R1_ AstraZeneca_20200327

Tramadol_V14R1_AstraZeneca_20200427

Lamivudine_V18R1_Simcyp_20200212

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