Search the PBPK Model Repository

Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

To contribute published user compound and/or population files, upload your files here: Upload Model Files

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You can use a * character as a wildcard at the end of a alphanumeric search term. The search term must start with at least one character before the wildcard. E.g., Rifam* will get you “Rifampicin” and “Rifampin”.
You can also use a * character as a wildcard in the middle of a alphanumeric search term. The search term must still start with at least one character before the wildcard. E.g., Rif*in will also get you “Rifampicin” and “Rifampin” .
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Found 110 Matches

Methotrexate_RES_V17R1_Simcyp_20180228

Model Files Publication

Simcyp developed Methotrexate compound file. Compound summary included. This was developed as a research file and its current status and limitations are outlined in summary document.

Search Score: 1

Propofol_RES_V18R1_Simcyp_20190529

Model Files Publication

Simcyp developed propofol compound file. Compound summary included. This was developed as a research file and its current status and limitations are outlined in the summary document.

Search Score: 1

Bergamottin_V19R1_AstraZeneca_20210423

Model Files Publication

CYP inhibitor found in grapefruit juice. AstraZeneca file.

Search Score: 1

Oncology_Population_V16R1_AstraZeneca_20190717

Model Files Publication

Oncology population from publication: Physiologically Based Pharmacokinetic Modeling for Olaparib Dosing Recommendations: Bridging Formulations, Drug Interactions, and Patient Populations Pilla Reddy, V., Bui, K., Scarfe, G., Zhou, D., Learoyd, M. (2018). Clinical Pharmacology and Therapeutics. https://doi.org/10.1002/cpt.1103 https://ascpt.onlinelibrary.wiley.com/doi/10.1002/cpt.1103

Search Score: 1

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Methotrexate_RES_V17R1_Simcyp_20180228

Propofol_RES_V18R1_Simcyp_20190529

Bergamottin_V19R1_AstraZeneca_20210423

Oncology_Population_V16R1_AstraZeneca_20190717

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