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Quickly find freely available drug and population models in our PBPK model repository.

The models provided have been collated from published examples which authors have shared in our Published Model Collection or developed as part of various global health projects in our Global Health Collection. This search facility searches both model collections simultaneously.

To contribute published user compound and/or population files, upload your files here: Upload Model Files

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Found 72 Matches

ValproicAcid_V21R1_NationalTaiwanUniversity_20231012

Model Files Publication

Three compound files for adults and 3 files for paediatrics are available for the parent compounds, Valproic Acid, reflecting the inputs required for EC tablets, tablets, and capsules, respectively. A compound file for the metabolite, 4-ene-Valproid Acid is available too. Details on the model assumptions and verification in V21R1 are available in the corresponding reference (DOI: 10.1002/psp4.13045) and supplement material on the journal (CPT: Pharmacometrics & Systems Pharmacology) website.

Physiologically based mechanistic insight into differential risk of valproate hepatotoxicity between children and adults: A focus on ontogeny impact - PubMed (nih.gov)

Search Score: 2

V18 released Simcyp files for antiretroviral drugs

Model Files Publication

V18 released Simcyp files for antiretroviral drugs

Search Score: 2

V19 Res Boosted Atazanavir April 2021

Model Files Publication

V19 Res Boosted Atazanavir April 2021

Search Score: 2

Vancomycin_V14R1_AstraZeneca_20200327

Model Files Publication

Vancomycin for pediatric predictions. https://ascpt.onlinelibrary.wiley.com/doi/full/10.1002/psp4.12101

Search Score: 2

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ValproicAcid_V21R1_NationalTaiwanUniversity_20231012

V18 released Simcyp files for antiretroviral drugs

V19 Res Boosted Atazanavir April 2021

Vancomycin_V14R1_AstraZeneca_20200327

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